Published in
Royal Society of Chemistry, RSC Advances, 52(7), p. 32877-32885, 2017
DOI: 10.1039/c7ra04922f
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Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists
Journal article published in 2017 by
Simona De Marino 
,
Adriana Carino ,
Dario Masullo,
Claudia Finamore ,
Valentina Sepe ,
Silvia Marchianò,
Francesco Saverio Di Leva ,
Vittorio Limongelli,
Stefano Fiorucci,
Angela Zampella
,
Adriana Carino ,
Dario Masullo,
Claudia Finamore ,
Valentina Sepe ,
Silvia Marchianò,
Francesco Saverio Di Leva ,
Vittorio Limongelli,
Stefano Fiorucci,
Angela Zampella
This paper is made freely available by the publisher.
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Abstract
Decoration of the bile acid side chain with an epoxide ring afforded potent and selective GPBAR1 agonists.