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Taylor and Francis Group, OncoImmunology, 2(2), p. e22987

DOI: 10.4161/onci.22987

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Retinoic acid-producing DCs and gut-tropic FOXP3+regulatory T cells in the induction of oral tolerance

Journal article published in 2013 by Eduardo J. Villablanca ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

The systemic unresponsiveness of the immune system to orally administered antigens is known as oral tolerance. Recent findings describe a new step for the induction of oral tolerance, consisting in the homing of FOXP3(+) regulatory T cells to the small bowel and the local acquisition of full immunosuppressive capacities, a process in which retinoic acid-producing dendritic cells might play a crucial role.