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Taylor and Francis Group, OncoImmunology, 2(2), p. e22984

DOI: 10.4161/onci.22984

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Role of c-MYC in tumor-associated macrophages and cancer progression

Journal article published in 2013 by Oscar M. Pello ORCID, Vicente Andrés
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Transcription factors of the MYC family regulate several homeostatic cell functions, and their role as proto-oncogenes has been the focus of interest for decades. We have recently demonstrated that c-MYC is expressed by tumor-associated macrophages (TAMs) and regulates their phenotype and pro-tumor activities in vivo.