Published in
American Association for the Advancement of Science, Science Signaling, 479(10), 2017
DOI: 10.1126/scisignal.aam5711
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Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes
Journal article published in 2017 by
Masahiro Nezu,
Tomokazu Souma 
,
Lei Yu,
Hiroki Sekine ,
Nobuyuki Takahashi ,
Andrew Zu-Sern Wei ,
Sadayoshi Ito,
Akiyoshi Fukamizu ,
Zsuzsanna K. Zsengeller ,
Tomohiro Nakamura,
Atsushi Hozawa,
S. Ananth Karumanchi,
Norio Suzuki ,
Masayuki Yamamoto
,
Lei Yu,
Hiroki Sekine ,
Nobuyuki Takahashi ,
Andrew Zu-Sern Wei ,
Sadayoshi Ito,
Akiyoshi Fukamizu ,
Zsuzsanna K. Zsengeller ,
Tomohiro Nakamura,
Atsushi Hozawa,
S. Ananth Karumanchi,
Norio Suzuki ,
Masayuki Yamamoto
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Abstract
ROS promote blood vessel formation in the placenta, which protects against preeclampsia.