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Oxford University Press, Stem Cells, 1(27), p. 78-87, 2009

DOI: 10.1634/stemcells.2008-0543

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Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors

Journal article published in 2009 by Slaven Erceg, Mohammad Ronaghi, Miodrag Stojković ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Human embryonic stem cells (hESCs) are self-renewing pluripotent cells that have the capacity to differentiate into a wide variety of cell types. This potentiality represents a promising source to overcome many human diseases by providing an unlimited supply of all cell types, including cells with neural characteristics. Therefore, this review summarizes early neural development and the potential of hESCs to differentiate under in vitro conditions, examining at the same time the potential use of differentiated hESCs for therapeutic applications for neural tissue and cell regeneration.