This paper proposes an area-efficient fully resistor- string digital-to-analog-converter (R-DAC)-based thin-film transistor liquid crystal display (TFT-LCD) column driver in which DACs supply only negative-polarity voltages, while polarity inverters generate positive-polarity voltages from negative-polarity voltages. An offset cancellation technique is employed in negative-polarity buffers and polarity inverters. An experimental prototype 8-bit column driver was implemented using 0.35-mu m CMOS technology to verify the proposed driving scheme. The settling time is within 5 mu s, and the maximum deviation is 0.68 LSB. The average area per channel is 0.04 mm(2). Compared with a conventional fully R-DAC-based TFT-LCD column driver, the proposed driving scheme has a DAC area saving of 41%. ; SCI