Published in

Oxford University Press (OUP), Bioinformatics, 6(25), p. 765-771

DOI: 10.1093/bioinformatics/btp053

Links

Tools

Export citation

Search in Google Scholar

Testing significance relative to a fold-change threshold is a TREAT

Journal article published in 2009 by Davis J. McCarthy, Gordon K. Smyth ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

Motivation: Statistical methods are used to test for the differential expression of genes in microarray experiments. The most widely used methods successfully test whether the true differential expression is different from zero, but give no assurance that the differences found are large enough to be biologically meaningful.