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Centers for Disease Control and Prevention, Emerging Infectious Diseases, 9(21), p. 1661-1663, 2015

DOI: 10.3201/eid2109.150104

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Disseminated Enteroviral Infection Associated with Obinutuzumab

Journal article published in 2015 by Claire Dendle, Michael Gilbertson, Tony M. Korman ORCID, Vera Golder, Eric Morand, Stephen Opat
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Two cases of disseminated enteroviral infection occurred in patients who received the CD20 monoclonal antibody obinutuzumab. Clinical features included hepatitis, edema, and a dermatomyositis-like syndrome. These manifestations may be unfamiliar to clinicians and are possibly responsive to intravenous immunoglobulin. Clinicians should remain vigilant for enteroviral infections in patients receiving obinutuzumab.