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American Society for Clinical Investigation, Journal of Clinical Investigation

DOI: 10.1172/jci67438

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Old King Coal — molecular mechanisms underlying an ancient treatment for atopic eczema

Journal article published in 2013 by W. H. Irwin McLean, Alan D. Irvine ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Traditional remedies for common disorders have been known for centuries, but insight into their mechanism of action is often limited. In this issue of the JCI, Joost Schalkwijk's research group at the Radboud. University Nijmegen Medical Centre in The Netherlands advances our understanding of why topical coal tar is an effective treatment for atopic dermatitis (AD), both rationalizing the use of this traditional medicine, and providing the scientific basis for new therapeutic approaches.