We report transport properties of single-crystalline Pd3Bi2S2, which has been predicted to host an unconventional electronic phase of matter beyond three-dimensional Dirac and Weyl semimetals. Similar to several topological systems, the resistivity shows field-induced metal to semiconductor-like crossover at low temperature. Large, anisotropic, and non-saturating magnetoresistance has been observed in the transverse experimental configuration. At 2 K and 9 T, the MR value reaches as high as ∼1.1 × 103%. Hall resistivity reveals the presence of two types of charge carriers and has been analyzed using the two-band model. In spite of the large density (>1021 cm−3), the mobility of charge carriers is found to be quite high (∼ 0.75 × 104 cm2 V−1 s−1 for the hole and ∼ 0.3 × 104 cm2 V−1 s−1 for the electron). The observed magneto-electrical properties indicate that Pd3Bi2S2 may be a new member of the topological semimetal family, which can have a significant impact in technological applications.