Published in
Association for Research in Vision and Ophthalmology, Investigative Ophthalmology & Visual Science, 10(53), p. 6389
DOI: 10.1167/iovs.12-9677
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
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Neuron-Specific Enolase Is Elevated in Asymptomatic Carriers of Leber's Hereditary Optic Neuropathy
Journal article published in 2012 by
Kenneth M. Yee,
Fred N. Ross-Cisneros,
Jeong Goo Lee,
Arlon Bastos Da Rosa,
Solange R. Salomao,
Adriana Berezovsky,
Rubens Belfort,
Filipe Chicani,
Milton Moraes-Filho,
Jerry Sebag,
Valerio Carelli 
,
Alfredo A. Sadun
,
Alfredo A. Sadun
This paper is made freely available by the publisher.
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Abstract
Asymptomatic carriers of LHON have higher serum NSE levels than affected and off-pedigree counterparts. Increased levels of serum NSE may be used as a biomarker to characterize RGC stress in LHON carriers.