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Royal Society of Chemistry, RSC Advances, 107(6), p. 105699-105712, 2016

DOI: 10.1039/c6ra20337j

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m-Cresol affects the lipid bilayer in membrane models and living neurons

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A preferential interaction ofm-cresol with high dipole-potential cholesterol/sphingomyelin-enriched lipid domains jeopardizes membrane integrity, explaining the toxicity ofm-cresol-containing insulin formulations.