Published in
Public Library of Science, PLoS ONE, 11(7), p. e49145, 2012
DOI: 10.1371/journal.pone.0049145
Links
- ORCID
- ORCID
- Public Library of Science
- [www.ncbi.nlm.nih.gov] | PDF
- [dare.ubvu.vu.nl] | PDF
- [www.cancerpharmacology.org] | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
Tools
High-Throughput MicroRNA (miRNAs) Arrays Unravel the Prognostic Role of MiR-211 in Pancreatic Cancer
,
Niccola Funel ,
Enrico Vasile,
Vittorio Perrone,
Leticia G. Leon,
Nelide De Lio,
Amir Avan,
Sara Caponi,
Luca E. Pollina,
Valentina Gallá,
Hiroko Sudo,
Alfredo Falcone,
Daniela Campani,
Ugo Boggi
and other authors.
Full text: Download
Abstract
Only a subset of radically resected pancreatic ductal adenocarcinoma (PDAC) patients benefit from chemotherapy, and identification of prognostic factors is warranted. Recently miRNAs emerged as diagnostic biomarkers and innovative therapeutic targets, while high-throughput arrays are opening new opportunities to evaluate whether they can predict clinical outcome. The present study evaluated whether comprehensive miRNA expression profiling correlated with overall survival (OS) in resected PDAC patients.