Background. Wider utilization of liver grafts from donors 70 years old could substan- tially expand the organ pool, but their use remains limited by fear of poorer outcomes. We examined the results at our center of liver transplantation (OLT) using livers from donors 70 years old. Methods. From February 2003 to August 2010, we performed 450 OLT including 58 (13%) using donors 70 whose outcomes were compared with those using donors 70 years old. Results. Cerebrovascular causes of death predominated among donors 70 (85% vs 47% in donors 70; P .001). In contrast, traumatic causes of death predominated among donors 70 (36% vs 14% in donors 70; P .002). Unlike grafts from donors 70 years old, grafts from older individuals had no additional risk factors (steatosis, high sodium, or hemodynamic instability). Both groups were comparable for cold and warm ischemia times. No difference was noted in posttransplant peak transaminases, incidence of primary nonfunction, hepatic artery thrombosis, biliary strictures, or retransplantation rates between groups. The 1- and 5-year patient survivals were 88% and 82% in recipients of livers 70 versus 90% and 84% in those from 70 years old ( P .705). Recipients of older grafts, who were 6 years older than recipients of younger grafts ( P .001), tended to have a lower laboratory Model for End-Stage Liver Disease score ( P .074). Conclusions. Short and mid-term survival following OLT using donors 70 yo can be excellent provided that there is adequate donor and recipient selection. Septuagenarians and octogenarians with cerebrovascular ischemic and bleeding accidents represent a large pool of potential donors whose wider use could substantially reduce mortality on the OLT waiting list. ; Peer reviewed