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Public Library of Science, PLoS ONE, 2(9), p. e87615, 2014

DOI: 10.1371/journal.pone.0087615

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Lactobacillus paracasei CBA L74 Metabolic Products and Fermented Milk for Infant Formula Have Anti-Inflammatory Activity on Dendritic Cells In Vitro and Protective Effects against Colitis and an Enteric Pathogen In Vivo

Journal article published in 2014 by Elena Zagato ORCID, Erika Mileti, Lucia Massimiliano, Francesca Fasano, Andrea Budelli, Giuseppe Penna, Maria Rescigno ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The rapid expansion of commercially available fermented food products raises important safety issues particularly when infant food is concerned. In many cases, the activity of the microorganisms used for fermentation as well as what will be the immunological outcome of fermented food intake is not known. In this manuscript we used complex in vitro, ex-vivo and in vivo systems to study the immunomodulatory properties of probiotic-fermented products (culture supernatant and fermented milk without live bacteria to be used in infant formula).