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Oxford University Press, Nucleic Acids Research, W1(43), p. W543-W546, 2015

DOI: 10.1093/nar/gkv385

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The iceLogo web server and SOAP service for determining protein consensus sequences

Journal article published in 2015 by Davy Maddelein, Niklaas Colaert, Iain Buchanan, Niels Hulstaert, Kris Gevaert ORCID, Lennart Martens
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The iceLogo web server and SOAP service implement the previously published iceLogo algorithm. iceLogo builds on probability theory to visualize protein consensus sequences in a format resembling sequence logos. Peptide sequences are compared against a reference sequence set that can be tailored to the studied system and the used protocol. As such, not only over- but also underrepresented residues can be visualized in a statistically sound manner, which further allows the user to easily analyse and interpret conserved sequence patterns in proteins. The web application and SOAP service can be found free and open to all users without the need for a login on http://iomics.ugent.be/icelogoserver/main.html.