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MyJove Corporation, Journal of Visualized Experiments, 65, 2012

DOI: 10.3791/3938-v

MyJove Corporation, Journal of Visualized Experiments, 65

DOI: 10.3791/3938

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Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain

Journal article published in 2012 by Marc Bettscheider, Arleta Kuczynska, Osborne Almeida ORCID, Dietmar Spengler
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Exposure to diet, drugs and early life adversity during sensitive windows of life 1,2 can lead to lasting changes in gene expression that contribute to the display of physiological and behavioural phenotypes. Such environmental programming is likely to increase the susceptibility to metabolic, cardiovascular and mental diseases 3,4.