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American Society of Hematology, Blood, 14(131), p. 1576-1586

DOI: 10.1182/blood-2017-07-798157

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Integrated molecular profiling of juvenile myelomonocytic leukemia

This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Data provided by SHERPA/RoMEO

Abstract

Key Points Targetable ALK/ROS1 tyrosine kinase fusions were detected in JMML patients without canonical RAS pathway mutations. Genome-wide methylation analysis identified the hypermethylation profile associated with poor clinical outcome.