Published in
SAGE Publications, Antiviral Therapy, 8(21), p. 739-742, 2015
DOI: 10.3851/imp3072
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Herpes virus reactivation after initiation of interferon-free antiviral agents in HIV–HCV-coinfected subjects: a new immune restoration disease?
Journal article published in 2016 by
Raffaella Marocco,
Miriam Lichtner,
Tiziana Tieghi,
Irene Pozzetto,
Claudio M. Mastroianni 
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
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Abstract
We report four HCV–HIV-coinfected patients who developed herpes zoster or muco-cutaneous herpes virus disease shortly after starting interferon-free antiviral treatment for HCV. We suggest that in our patients the prompt clearance of HCV following direct-acting antivirals leads to a paradoxical effect on the innate and adaptive immune system mediating the reactivation of herpetic infection.