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American Association for the Advancement of Science, Science Advances, 7(4), 2018

DOI: 10.1126/sciadv.aat0979

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Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate–mediated membrane permeabilization

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Human β-defensin 2 permeabilizes and kills fungal cells by specifically targeting the important plasma membrane lipid PIP 2 .