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Royal Society of Chemistry, RSC Advances, 16(7), p. 9461-9464, 2017

DOI: 10.1039/c6ra26546d

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Oxidation of diazenyl-protected N-heterocycles – a new entry to functionalized lactams

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A strategy for the synthesis ofN-aryldiazenyllactams, offering the direct access to protected lactam derivatives, is based on the oxidation of the corresponding cyclic amines with a ruthenium-based catalyst in CCl4/CAN/phosphate buffer.