Dissemin is shutting down on January 1st, 2025

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American Society of Hematology, Blood, 6(128), p. 805-815, 2016

DOI: 10.1182/blood-2016-01-694117

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Dimethyl fumarate restores apoptosis sensitivity and inhibits tumor growth and metastasis in CTCL by targeting NF-κB

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points DMF induces specific cell death in CTCL cells and inhibits CTCL tumor growth and metastasis in vivo via inhibition of NF-κB. DMF therefore represents a promising, nontoxic novel therapeutic approach to treating CTCL.