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American Society of Hematology, Blood, 8(129), p. 950-958, 2017

DOI: 10.1182/blood-2016-06-720649

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Cytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Key Points RNA interference screen targeted to primary human HSPCs identified CYTH1 as a crucial mediator of cell adhesion. CYTH1 is required for homing and proper bone marrow localization of HSPCs following transplantation.