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Elsevier, Journal of Biological Chemistry, 29(286), p. 25443-25449, 2011

DOI: 10.1074/jbc.r110.199703

Humana Press, Methods in Molecular Biology, p. 189-205, 2009

DOI: 10.1007/978-1-60761-157-8_11

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Liquid Chromatography-Mass Spectrometry-based Quantitative Proteomics*

Journal article published in 2009 by Fang Xie, Michael W. Linscheid, Wei-Jun Qian, Tao Liu, Robert Ahrends ORCID, Stefan Pieper, Richard D. Smith ORCID, Vladislav A. Petyuk, Andreas Kühn
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

LC-MS-based quantitative proteomics has become increasingly applied to a wide range of biological applications due to growing capabilities for broad proteome coverage and good accuracy and precision in quantification. Herein, we review the current LC-MS-based quantification methods with respect to their advantages and limitations and highlight their potential applications.