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Oxford University Press, Open Forum Infectious Diseases, 1(4), 2016

DOI: 10.1093/ofid/ofw245

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Delayed diagnosis of tuberculous meningitis misdiagnosed as herpes simplex virus-1 encephalitis with the filmarray syndromic polymerase chain reaction panel

Journal article published in 2016 by Carlos A. Gomez, Benjamin A. Pinsky ORCID, Anne Liu, Niaz Banaei
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract The FilmArray meningitis/encephalitis (ME) panel is a novel syndromic, nucleic acid amplification test for diagnosis of acute meningitis and encephalitis. Emerging data on its performance are concerning for false-positive results. We present a case of tuberculous meningitis misdiagnosed as herpes simplex virus-1 encephalitis with the FilmArray ME panel. Strategies to mitigate erroneous results are discussed.