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American Society for Microbiology, Infection and Immunity, 9(71), p. 5398-5401, 2003

DOI: 10.1128/iai.71.9.5398-5401.2003

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Nicotinamide Ribosyl Uptake Mutants in Haemophilus influenzae

Journal article published in 2003 by Mark Herbert, Elizabeta Sauer, Graeme Smethurst, Anita Kraiss, Anita Kraiβ, Anna-Karina Hilpert, Joachim Reidl ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT The gene for the nicotinamide riboside (NR) transporter ( pnuC ) was identified in Haemophilus influenzae . A pnuC mutant had only residual NR uptake and could survive in vitro with high concentrations of NR, but could not survive in vivo. PnuC may represent a target for the development of inhibitors for preventing H. influenzae disease.