Intracystic interferon-alpha in pediatric craniopharyngioma patients: an international multicenter assessment on behalf of SIOPE and ISPN
Journal article published in 2017 by
John-Paul Kilday,
Massimo Caldarelli,
Luca Massimi,
Robert Hsin-Hung Chen,
Yi Yen Lee,
Muh-Lii Liang,
Jeanette Parkes 
,
Thuran Naiker,
Marie-Lise van Veelen ,
Erna Michiels,
Conor Mallucci,
Benedetta Pettorini,
Lisethe Meijer,
Christian Dorfer ,
Thomas Czech
and other authors.
,
Thuran Naiker,
Marie-Lise van Veelen ,
Erna Michiels,
Conor Mallucci,
Benedetta Pettorini,
Lisethe Meijer,
Christian Dorfer ,
Thomas Czech
and other authors.
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Abstract
Craniopharyngiomas are frequent hypothalamo-pituitary tumors in children, presenting predominantly as cystic lesions. Morbidity from conventional treatment has focused attention on intracystic drug delivery, hypothesized to cause fewer clinical consequences. However, the efficacy of intracystic therapy remains unclear. We report the retrospective experiences of several global centers using intracystic interferon-alpha.