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American Association for the Advancement of Science, Science Signaling, 423(9), 2016

DOI: 10.1126/scisignal.aad2429

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Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease

Journal article published in 2016 by Arthur Marivin, Anthony Leyme, Kshitij Parag-Sharma ORCID, Vincent DiGiacomo, Anthony Y. Cheung, Lien T. Nguyen, Isabel Dominguez, Mikel Garcia-Marcos
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Mutations in the G protein subunit Gα i3 prevent the endothelin receptor from coupling to the appropriate G protein in patients with auriculo-condylar syndrome.