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American Society of Hematology, Blood, 14(128), p. 1879-1883, 2016

DOI: 10.1182/blood-2016-05-716092

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Altered fibrinolysis in autosomal dominant thrombomodulin-associated coagulopathy.

Journal article published in 2016 by Kate Burley, Claire S. Whyte, Sarah K. Westbury, Mary Walker, Kathleen E. Stirrups, Oliver G. Chapman, Christopher Reilly-Stitt, Ernest Turro ORCID, Nicola J. Mutch, Andrew D. Mumford
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points TM-AC is a heritable bleeding disorder in which high plasma TM levels reduce thrombin generation. High plasma TM levels also delay clot lysis by enhancing TM/thrombin-mediated activation of TAFI.