Published in
American Association for the Advancement of Science, Science Translational Medicine, 339(8), 2016
DOI: 10.1126/scitranslmed.aad3099
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The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia
Journal article published in 2016 by
Gabriela Brumatti,
Chunyan Ma,
Najoua Lalaoui,
Nhu-Y. Nguyen,
Mario Navarro,
Maria C. Tanzer,
Jennifer Richmond,
Margherita Ghisi,
Elisha de Valle,
Natasha Silke,
Giovanna Pomilio,
Jessica M. Salmon 
,
Stefan P. Glaser,
Raffi Gugasyan,
Mark A. Gurthridge
and other authors.
,
Stefan P. Glaser,
Raffi Gugasyan,
Mark A. Gurthridge
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
The combination of a SMAC mimetic and a caspase inhibitor kills AML cells by inducing necroptosis.