Published in
SAGE Publications, Natural Product Communications, 11(7), p. 1934578X1200701, 2012
DOI: 10.1177/1934578x1200701117
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Rotenoid derivatives from Derris trifoliata with nitric oxide production inhibitory activity
Journal article published in 2012 by
Chihiro Ito,
Tomiyasu Murata,
Hugh T.-W. Tan 
,
Norio Kaneda,
Hiroshi Furukawa,
Masataka Itoigawa
,
Norio Kaneda,
Hiroshi Furukawa,
Masataka Itoigawa
This paper is made freely available by the publisher.
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Abstract
Study of the chemical constituents of the stems of Derris trifoliata Lour. (Leguminosae) collected in Singapore led to the isolation and identification of three known and two new rotenoid derivatives. The new derivatives, named derrisfolin A (1) and B (2), inhibited nitric oxide production in murine macrophage-like RAW 264.7 cells stimulated with interferon-γ and lipopolysaccharide.