Published in
Impact Journals, Oncotarget, 9(8), p. 15704-15715, 2017
DOI: 10.18632/oncotarget.14944
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Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitro
Journal article published in 2017 by
Romina Salpini,
Matteo Surdo,
Nadia Warner,
Maria Francesca Cortese 
,
Danny Colledge,
Sally Soppe,
Mc Bellocchi,
Daniele Armenia,
Luca Carioti,
Fabio Continenza,
Domenico Di Carlo,
Domenico Di Carlo,
Patrizia Saccomandi,
Carmen Mirabelli,
Michela Pollicita
and other authors.
,
Danny Colledge,
Sally Soppe,
Mc Bellocchi,
Daniele Armenia,
Luca Carioti,
Fabio Continenza,
Domenico Di Carlo,
Domenico Di Carlo,
Patrizia Saccomandi,
Carmen Mirabelli,
Michela Pollicita
and other authors.
This paper is made freely available by the publisher.
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Abstract
An impaired HBsAg-secretion can increase HBV oncogenic-properties. Here, we investigate genetic-determinants in HBsAg correlated with HBV-induced hepatocellular carcinoma (HCC), and their impact on HBsAg-secretion and cell-proliferation.