Purpose: To compare Herman scores self-assessed prospectively during ultrasound firsttrimester screening by a single senior radiologist with 15 years of experience, to those obtained retrospectively by an unexperienced junior radiologist. Materials and methods: Over a 18-month period, a single senior radiologist measured the nuchal translucency thickness along with calculation of Herman scores. An independent junior radiologist subsequently reviewed and scored the images. Results: A total of 301 patients were included. The mean Herman score was 8.2 +/- 0.9 (SD) for the senior radiologist and 7.8 +/- 0.9 (SD) after review by the independent junior radiologist (P