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American Society of Hematology, Blood, 2(128), p. 277-285, 2016

DOI: 10.1182/blood-2015-10-677054

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von Willebrand factor multimerization and the polarity of secretory pathways in endothelial cells

Journal article published in 2016 by Mafalda Lopes da Silva ORCID, Daniel F. Cutler ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key PointsThe 3 endothelial secretory pathways—constitutive, basal, and regulated—release VWF in different multimeric states. Apical- and basolaterally-released VWF follow different secretory pathways, thus releasing differentially multimerized protein.