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Wiley, Angewandte Chemie, 47(125), p. 12524-12528, 2013

DOI: 10.1002/ange.201305482

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Neural stem cells harvested from live brains by antibody-conjugated magnetic nanoparticles.

Journal article published in 2013 by Cn N. P. Lui, Yp P. Tsui, As S. L. Ho, Dk K. Y. Shum, Ys S. Chan, Ct T. Wu, Hw W. Li ORCID, Sc C. Edman Tsang, Kk K. L. Yung
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

It stems from the magnetism: The extraction of stem/progenitor cells from the brain of live animals is possible using antibodies conjugated to magnetic nanoparticles (Ab-MNPs). The Ab-MNPs are introduced to a rat's brain with a superfine micro-syringe. The stem cells attach to the Ab-MNPs and are magnetically isolated and removed. They can develop into neurospheres and differentiate into different types of cells outside the subject body. The rat remains alive and healthy.