In this paper the influence of obstructions on microchannel electro-osmotic flow is investigated for the first time. To carry out such a study, regular obstructions are introduced into microchannels and flow rates are numerically calculated. The effect of channel width on flow rates is analysed on both free and obstructed channels. The solid material considered for channel walls and obstructions is silicon, and the electrolyte is deionised water. The parameters studied include channel width, obstruction size and effective porosity of the channel. The effective porosity is varied between 0.4 and 0.8 depending on other chosen parameters. The results clearly demonstrate that, under the analysed conditions, introduction of obstructions into channels wider than $100\,\upmu \hbox {m}$ 100μm enhances the flow rate induced by electro-osmosis.