Published in
Oxford University Press, The American Journal of Clinical Nutrition, 2(105), p. 400-410, 2017
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- Oxford University Press
- [www.ncbi.nlm.nih.gov] | PDF
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- [www.ncbi.nlm.nih.gov] | PDF
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Effects of supplementation with nondigestible carbohydrates on fecal calprotectin and on epigenetic regulation of SFRP1 expression in the large-bowel mucosa of healthy individuals12
Journal article published in 2017 by
Fiona C. Malcomson 
,
Naomi D. Willis,
Iain McCallum,
Long Xie,
Idoia Ibero-Baraibar,
Wing C. Leung,
Seamus Kelly,
D. Michael Bradburn,
Nigel J. Belshaw,
Ian T. Johnson,
John C. Mathers
,
Naomi D. Willis,
Iain McCallum,
Long Xie,
Idoia Ibero-Baraibar,
Wing C. Leung,
Seamus Kelly,
D. Michael Bradburn,
Nigel J. Belshaw,
Ian T. Johnson,
John C. Mathers
This paper is made freely available by the publisher.
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Abstract
Background: Hyperactive Wnt signaling is frequently observed in colorectal cancer. Higher intakes of dietary fiber [nondigestible carbohydrates (NDCs)] and the fermentation product butyrate are protective against colorectal cancer and may exert their preventative effects via modulation of the Wnt pathway.