Generation of functional human hepatic endoderm from human induced pluripotent stem cells
Journal article published in 2009 by
Gareth J. Sullivan,
David C. Hay,
In-Hyun Park,
Judy Fletcher,
Zara Hannoun,
Catherine M. Payne,
Donna Dalgetty,
James R. Black,
James A. Ross,
Kay Samuel,
Gang Wang,
George Q. Daley,
Je-Hyuk Lee,
George M. Church,
Stuart J. Forbes 
and other authors.
and other authors.
This paper is available in a repository.
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Abstract
With the advent of induced pluripotent stem cell (iPSC) technology, it is now feasible to generate iPSCs with a defined genotype or disease state. When coupled with direct differentiation of defined lineage, such as hepatic endoderm (HE). iPSC would revolutionise the way we study human liver biology and generate efficient “off the shelf” models of human liver disease.