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Wiley, Angewandte Chemie, 18(125), p. 4890-4894, 2013

DOI: 10.1002/ange.201209127

Wiley, Angewandte Chemie International Edition, 18(52), p. 4790-4794, 2013

DOI: 10.1002/anie.201209127

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A Protein-Interaction Array Inside a Living Cell**

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Taking the bait: Protein interaction arrays were generated in living cells by the interaction of bait-presenting artificial receptor constructs (bait-PARCs) with micrometer-scaled antibody surface patterns. This method was applied to simultaneously monitor the interaction kinetics of a prey protein with two distinct bait proteins in individual living cells.