Published in
Oxford University Press (OUP), Clinical Infectious Diseases, 6(60), p. 881-888
DOI: 10.1093/cid/ciu940
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Astrovirus VA1/HMO-C: An Increasingly Recognized Neurotropic Pathogen in Immunocompromised Patients
Journal article published in 2015 by
Julianne R. Brown 
,
Sofia Morfopoulou ,
Jonathan Hubb,
Warren A. Emmett,
Winnie Ip,
Divya Shah,
Tony Brooks,
Simon M. L. Paine,
Glenn Anderson,
Alex Virasami,
Cy Y. William Tong,
Duncan A. Clark,
Vincent Plagnol ,
Thomas S. Jacques,
Waseem Qasim
and other authors.
,
Sofia Morfopoulou ,
Jonathan Hubb,
Warren A. Emmett,
Winnie Ip,
Divya Shah,
Tony Brooks,
Simon M. L. Paine,
Glenn Anderson,
Alex Virasami,
Cy Y. William Tong,
Duncan A. Clark,
Vincent Plagnol ,
Thomas S. Jacques,
Waseem Qasim
and other authors.
This paper is made freely available by the publisher.
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Abstract
Brain biopsy from a child with unknown cause of encephalopathy was deep-sequenced. Astrovirus VA1/HMO-C was identified, highly divergent from human astroviruses and 95% identical to astrovirus previously associated with encephalitis. Findings suggest astrovirus VA1/HMO-C is an under-recognized cause of viral encephalitis.