Introduction. The objective of this study was to cross-culturally adapt and validate ICS male SF questionnaire to Serbian language.Materials and Methods. This study included 91 male patients with lower urinary tract symptoms and 24 men with similar age and with confirmed absence of LUTS. ICS male SF questionnaire was translated from English to Serbian language and then back-translated to English.Results. Internal consistency was high in both dimensions, voiding (Cronbach’s alpha = 0.916) and incontinence (Cronbach’s alpha = 0.763). Comparison of the average scores between patients and controls revealed significant differences in both dimensions: voiding (med = 8 versus med = 0;P<0.001) and incontinence (med = 3 versus med = 0;P<0.001). Interclass correlation revealed high testretest validity in both dimensions, voiding ICC = 0.992P<0.001and incontinece ICC = 0.989P<0.001. Correlation analysis revealed high agreement between ICS male SF voiding dimension and IPSS questionnaire (ρ=0.943;P<0.001).Conclusion. The Serbian version of male ICS SF questionnaire showed acceptable reliability and validity. The ICS male SF questionnaire could be used in routine practice as an easy and comprehensive tool for assessment of LUTS.