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Wiley, FEBS Letters, 21(583), p. 3377-3387, 2009

DOI: 10.1016/j.febslet.2009.09.051

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Deceptively simple but simply deceptive - Caenorhabditis elegans lifespan studies: Considerations for aging and antioxidant effects

Journal article published in 2009 by Jan Gruber, Li Fang Ng, Barry Halliwell, Suresh Kumar Poovathingal ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The nematode worm Caenorhabditis elegans (C. elegans) is increasingly popular as a model organism for aging studies as well as for testing antioxidants and other compounds for effects on longevity. However, results in the literature are sometimes confusing and contradictory. This review introduces C. elegans as a model organism, discusses aspects that make it attractive for aging and antioxidant research, and addresses some problems and potential artifacts.