Dissemin is shutting down on January 1st, 2025

Published in

Wiley Open Access, Journal of Cellular and Molecular Medicine, 1(13), p. 24-38, 2008

DOI: 10.1111/j.1582-4934.2008.00534.x

Links

Tools

Export citation

Search in Google Scholar

Advances in microRNAs: implications for immunity and inflammatory diseases

Journal article published in 2008 by E. Sonkoly, A. Pivarcsi ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Since their discovery in 1993 and the introduction of the term microRNA in 2001, it has become evident that microRNAs (miRNAs) involved in many biological processes, including development, differentiation, proliferation and apoptosis. The function of miRNA the control of protein production in cells by sequence-specific targeting of mRNAs for translational repression or mRNA degradati Interestingly, immune genes are apparently preferentially targeted by miRNAs compared to the average of the human genome, indicat the significance of miRNA-mediated regulation for normal immune responses. Here, we review what is known about the role of miRN in the pathogenesis of immune-related diseases such as chronic inflammatory skin diseases, autoimmunity and viral infections.