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BioMed Central, Parasites and Vectors, 1(1), 2008

DOI: 10.1186/1756-3305-1-35

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Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites

Journal article published in 2008 by Xia Wang, Momodou Jobe, Kevin M. Tyler, Dietmar Steverding ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract The disinfectants TriGene, bleach, ethanol and liquid hand soap, and water and temperature were tested for their ability to kill bloodstream forms of Trypanosoma brucei , epimastigotes of Trypanosoma rangeli and promastigotes of Leishmania major . A 5-min exposure to 0.2% TriGene, 0.1% liquid hand soap and 0.05% bleach (0.05% NaOCl) killed all three trypanosomatids. Ethanol and water destroyed the parasites within 5 min at concentrations of 15–17.5% and 80–90%, respectively. All three organisms were also killed when treated for 5 min at 50°C. The results indicate that the disinfectants, water and temperature treatment (i.e. autoclaving) are suitable laboratory hygiene measures against trypanosomatid parasites.