Sphingosine Kinase 1 Is Regulated by Peroxisome Proliferator-activated Receptor α in Response to Free Fatty Acids and Is Essential for Skeletal Muscle Interleukin-6 Production and Signaling in Diet-induced Obesity*
Journal article published in 2013 by
Jessica S. Ross,
Wei Hu,
Bess Rosen,
Ashley J. Snider,
Lina M. Obeid 
,
L. Ashley Cowart
,
L. Ashley Cowart
This paper is made freely available by the publisher.
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Abstract
Background: The fatty acid palmitate induces sphingosine kinase 1 (Sphk1) activity in skeletal muscle by an unknown mechanism.