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BioMed Central, Journal of Clinical Bioinformatics, 1(1), p. 7, 2011

DOI: 10.1186/2043-9113-1-7

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Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels

Journal article published in 2011 by Melinda Rezeli, Ákos Végvári ORCID, Thomas E. Fehniger, Thomas Laurell, György Marko-Varga
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A perspective overview is given describing the current development of multiplex mass spectrometry assay technology platforms utilized for high throughput clinical sample analysis. The development of targeted therapies with novel personalized medicine drugs will require new tools for monitoring efficacy and outcome that will rely on both the quantification of disease progression related biomarkers as well as the measurement of disease specific pathway/signaling proteins.