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BioMed Central, Genome Biology, 2(10), p. 402

DOI: 10.1186/gb-2009-10-2-402

BioMed Central, Genome Biology, 3(8), p. R39

DOI: 10.1186/gb-2007-8-3-r39

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Reactome: a knowledge base of biologic pathways and processes

Journal article published in 2007 by Imre Vastrik, Peter D'Eustachio ORCID, Esther Schmidt, Geeta Joshi-Tope, Gopal Gopinath, David Croft, Bernard de Bono, Marc Gillespie ORCID, Bijay Jassal, Suzanna Lewis, Lisa Matthews, Guanming Wu, Peter D. Eustachio, Bernard Bono, Ewan Birney ORCID and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Reactome http://www.reactome.org , an online curated resource for human pathway data, provides infrastructure for computation across the biologic reaction network. We use Reactome to infer equivalent reactions in multiple nonhuman species, and present data on the reliability of these inferred reactions for the distantly related eukaryote Saccharomyces cerevisiae . Finally, we describe the use of Reactome both as a learning resource and as a computational tool to aid in the interpretation of microarrays and similar large-scale datasets.