Published in
BMJ Publishing Group, Journal of Medical Genetics, 9(41), p. 658-663, 2004
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults
Journal article published in 2004 by
H. E. Wichmann,
N. Klopp,
S. Wagenpfeil,
L. Rummler,
M. Schedel,
M. Kabesch,
T. Schafer,
T. Schäfer,
U. Darsow,
T. Jakob,
H. Behrendt,
J. Ring,
S. Weidinger 
,
T. Illig
,
T. Illig
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Abstract
Background: Several studies have shown linkage of chromosome 12q 13–24 with atopy related phenotypes. Among candidate genes in this region is STAT6 (signal transducer and activator of transcription), which is essential for Th2 cell differentiation, recruitment, and effector function.