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Elsevier, Year Book of Neonatal and Perinatal Medicine, (2008), p. 127-128

DOI: 10.1016/s8756-5005(08)79022-x

American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 12(174), p. 1370-1377, 2006

DOI: 10.1164/rccm.200605-676oc

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Superoxide Dismutase Improves Oxygenation and Reduces Oxidation in Neonatal Pulmonary Hypertension

Journal article published in 2006 by Satyan Lakshminrusimha, James A. Russell, Stephen Wedgwood, Sylvia F. Gugino, Jeffrey A. Kazzaz, Jonathan M. Davis, Robin H. Steinhorn ORCID, K. Van Meurs
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Rationale: Hyperoxic ventilation in the management of persistent pulmonary hypertension of the newborn (PPHN) can result in the formation of reactive oxygen species, such as superoxide anions, which can inactivate nitric oxide (NO) and cause vasoconstriction and oxidation.