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American Academy of Neurology (AAN), Neurology, 9(83), p. 818-825

DOI: 10.1212/wnl.0000000000000745

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Prefrontal involvement related to cognitive impairment in progressive muscular atrophy

Journal article published in 2014 by Joost Raaphorst, Marie-José van Tol, Paul F. C. Groot, P. F. C. de Groot, Ellemarije Altena, M. J. van Tol, Ysbrand D. van der Werf ORCID, P. F. M. Groot, Charles B. Majoie, Anneke J. van der Kooi, Y. D. van der Werf, Leonard H. van den Berg, A. J. van der Kooi, L. H. van den Berg, Ben A. Schmand and other authors.
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This paper is available in a repository.

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Abstract

OBJECTIVE: To examine brain activation patterns during verbal fluency performance in patients with progressive muscular atrophy (PMA) and amyotrophic lateral sclerosis (ALS). METHODS: fMRI was used to examine the blood oxygen level-dependent response during letter and category fluency performance in 18 patients with PMA, 21 patients with ALS, and 17 healthy control subjects, matched for age and education. fMRI results are reported at p